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Charleston is located just south of the mid-point of South Carolina's coast line, at the confluence of the Ashley and Cooper Rivers. Charleston's name is derived from Charles Towne, named after King Charles II of England. It is the largest city and county seat of Charleston County. The city was founded as Charlestown or Charles Towne in 1670, and moved to its present location (Oyster Point) from a location on the west bank of the Ashley River in 1680; it adopted its present name in 1783. In 1690, Charleston was the fifth largest city in North America, and remained among the ten largest cities in the United States through the 1840 census. Charleston is known as The Holy City due to the prominence of churches on the low-rise cityscape, particularly the numerous steeples which dot the city's skyline. The population was estimated to be 118,492 in 2007, making it the second most populous city in South Carolina closely behind the state capital Columbia. Downtown offers a wide selection of homes for sale, from massive single family homes to large condos. Pricing is often viewed as being on a sliding scale from the Battery, where the beautiful, carefully restored colonial homes often begin in the million dollar range, to the modest Charleston Singles and town homes in the northwest portion of the peninsula near the Crosstown, where prices are much lower. The area above the Crosstown has older homes that are being renovated.

Local points of interest include Cooper River Bridge Run, The Battery, Charleston Waterfront Park, Charleston Ghost Tours, Meeting Street Bed and Breakfast, Market Street, Beautiful Churches, South Carolina Aquarium, Downtown Shopping, The Spoleto Festival, Great Restaurants, Medical University of South Carolina, College of Charleston, Charleston School of Law, The Provost Dungeon, Roper Hospital, The Citadel, Hampton Park, Joe Riley Stadium, and Fort Sumter.